› 6xte

X-ray diffraction
2.27Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126263 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin-5 Chain: A
Molecule details ›
Chain: A
Length: 1096 amino acids
Theoretical weight: 123.7 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: O00410 (Residues: 4-1097; Coverage: 100%)
Gene names: IPO5, KPNB3, RANBP5
Sequence domains:
Antipain Chain: C
Molecule details ›
Chain: C
Length: 4 amino acids
Theoretical weight: 607 Da
Source organism: Actinomycetes

Ligands and Environments

2 bound ligands:
Ligand NI 2 x NI
Ligand CL 1 x CL
3 modified residues:
Ligand CSO 1 x CSO
Ligand FC0 1 x FC0
Ligand RGL 1 x RGL

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 87.091Å b: 96.313Å c: 156.979Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.199 0.26
Expression system: Trichoplusia ni

Quick links

Citations

2 review citations

How SARS-CoV-2 and Other Viruses Build an Invasion Route to Hijack the Host Nucleocytoplasmic Trafficking System.
Sajidah et al. (2021)
1 more