› 6xtj

X-ray diffraction
1.6Å resolution

The high resolution structure of the FERM domain of human FERMT2

Released:
DOI: 10.2210/pdb6xtj/pdb
PDB entry 6xtj coloured by chain, front view.
PDB entry 6xtj coloured by chain, side view.
PDB entry 6xtj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bradshaw WJ, Katis VL, Newman JA, von Delft F, Arrowsmith CH, Edwards A, Bountra C, Gileadi O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fermitin family homolog 2 Chain: AAA
Molecule details ›
Chain: AAA
Length: 478 amino acids
Theoretical weight: 55.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96AC1 (Residues: 8-680; Coverage: 70%)
Gene names: FERMT2, KIND2, MIG2, PLEKHC1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand CIT 3 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3221
Unit cell:
a: 145.172Å b: 145.172Å c: 59.633Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.181 0.204
Expression system: Escherichia coli BL21(DE3)

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