6xw6

X-ray diffraction
1.96Å resolution

Crystal structure of murine norovirus P domain in complex with Nanobody NB-5853

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-212521 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Capsid protein VP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 307 amino acids
Theoretical weight: 33.41 KDa
Source organism: Murine norovirus 1
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q80J94 (Residues: 228-533; Coverage: 57%)
Gene name: ORF2
Sequence domains: Calicivirus coat protein C-terminal
Nanobody NB-5853 Chains: C, D
Molecule details ›
Chains: C, D
Length: 134 amino acids
Theoretical weight: 14.84 KDa
Source organism: Vicugna pacos
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-3
Spacegroup: P21
Unit cell:
a: 72.69Å b: 85.29Å c: 77.97Å
α: 90° β: 113.47° γ: 90°
R-values:
R R work R free
0.202 0.199 0.248
Expression systems:
  • Escherichia coli BL21
  • Escherichia coli