› 6y43

X-ray diffraction
1.6Å resolution

Fibrinogen-like globe domain of human ANGPTL6

Released:
DOI: 10.2210/pdb6y43/pdb
PDB entry 6y43 coloured by chain, front view.
PDB entry 6y43 coloured by chain, side view.
PDB entry 6y43 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Coker JA, Krojer T, Mutisya JM, Arrowsmith CH, Bountra C, Midwood KS, Yue WW, Marsden BD, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185577 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiopoietin-related protein 6 Chain: A
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 25.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NI99 (Residues: 251-470; Coverage: 49%)
Gene names: AGF, ANGPTL6, ARP5, UNQ152/PRO178
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand EDO 3 x EDO
Ligand EPE 1 x EPE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 39.382Å b: 65.111Å c: 76.306Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.172 0.208
Expression system: Escherichia coli

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