› 6y4z

X-ray diffraction
1.9Å resolution

The crystal structure of human MACROD2 in space group P43212

Released:
DOI: 10.2210/pdb6y4z/pdb
PDB entry 6y4z coloured by chain, front view.
PDB entry 6y4z coloured by chain, side view.
PDB entry 6y4z coloured by chain, top view.
Source organisms:
Primary publication:
Multiple crystal forms of human MacroD2.
Wazir S, Maksimainen MM, Lehtiö L
Acta Crystallogr F Struct Biol Commun 76 477-482 (2020)
PMID: 33006575

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106765 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribose glycohydrolase MACROD2; Thioredoxin 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 366 amino acids
Theoretical weight: 40.91 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AA25 (Residues: 1-109; Coverage: 100%)
  • Canonical: A1Z1Q3 (Residues: 7-243; Coverage: 56%)
Gene names: C20orf133, JW5856, MACROD2, b3781, fipA, trxA, tsnC
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand TLA 1 x TLA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P43212
Unit cell:
a: 95.36Å b: 95.36Å c: 261.92Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.228
Expression system: Escherichia coli

Quick links

Citations

1 mention without citation

Multiple crystal forms of human MacroD2.
Wazir et al. (2020)