Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Sequence domains:
- Proteasome component (PCI) domain
- Small ribosomal subunit protein uS2
- Eukaryotic translation initiation factor 3 subunit D
- Eukaryotic translation initiation factor 3 subunit E
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS27
- JAB1/MPN/MOV34 metalloenzyme domain
54 more domains
Structure analysis Details
Assembly composition:
hetero nonadecamer (preferred)
PDBe Complex ID:
PDB-CPX-126238 (preferred)
Entry contents:
19 distinct polypeptide molecules
Macromolecules (19 distinct):