PDB 6ycs structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Biochemical function:

transcription coactivator activity

Biological process:

positive regulation of transcription initiation by RNA polymerase II

Cellular component:

not assigned

Sequence domains:

Structure analysis Details

Assembly composition:

hetero hexamer (preferred)

Assembly name:

Activated RNA polymerase II transcriptional coactivator p15 and DNA (preferred)

PDBe Complex ID:

PDB-CPX-120991 (preferred)

Entry contents:

1 distinct polypeptide molecule
2 distinct DNA molecules

Macromolecules (3 distinct):

Activated RNA polymerase II transcriptional coactivator p15 Chains: A, B, C, D

Molecule details ›

Chains: A, B, C, D
Length: 72 amino acids
Theoretical weight: 8.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

Canonical: P53999 (Residues: 61-127; Coverage: 53%)

Gene names: PC4, RPO2TC1, SUB1
Sequence domains: Transcriptional Coactivator p15 (PC4)

DNA (5'-D(P*(OKQ))-D(P*(OKT))-R(P*(RFJ))-D(*(OKQ)P*(OKT)P*(AS)P*(GS)P*(OKN)P*(OKN)P*(PST)P*(OKN)P*(PST)P*(GS)P*(GS)P*(AS)P*(OKT)P*(OKT))-3') Chain: E

Molecule details ›

Chain: E
Length: 17 nucleotides
Theoretical weight: 5.96 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(P*(OKQ))-D(P*(OKT))-R(P*(RFJ))-D(*(OKQ)P*(OKT)P*(AS)P*(GS)P*(OKN)P*(OKN)P*(PST)P*(OKN)P*(PST)P*(GS)P*(GS)P*(AS)P*(OKT)P*(OKT))-3') Chain: F

Molecule details ›

Chain: F
Length: 17 nucleotides
Theoretical weight: 5.8 KDa
Source organism: synthetic construct
Expression system: Not provided