› 6yhz

Solution NMR

UvrD helicase RNA polymerase interactions are governed by UvrDs carboxy terminal Tudor domain.

Released:
DOI: 10.2210/pdb6yhz/pdb
PDB entry 6yhz coloured by chain, ensemble of 10 models, front view.
PDB entry 6yhz coloured by chain, ensemble of 10 models, side view.
PDB entry 6yhz coloured by chain, ensemble of 10 models, top view.
Source organism: Escherichia coli
Primary publication:
UvrD helicase-RNA polymerase interactions are governed by UvrD's carboxy-terminal Tudor domain.
Kawale AA, Burmann BM
Commun Biol 3 607 (2020)
PMID: 33097771

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151850 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription-repair-coupling factor Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.11 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P30958 (Residues: 472-547; Coverage: 7%)
Gene names: JW1100, b1114, mfd
Sequence domains: CarD-like/TRCF RID domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

8 citation in other articles

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.
Urrutia-Irazabal et al. (2021)
7 more