› 6yj6

Electron Microscopy
3.1Å resolution

Structure of the TFIIIC subcomplex tauA

Released:
DOI: 10.2210/pdb6yj6/pdb
PDB entry 6yj6 coloured by chain, front view.
PDB entry 6yj6 coloured by chain, side view.
PDB entry 6yj6 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation.
Vorländer MK, Jungblut A, Karius K, Baudin F, Grötsch H, Kosinski J, Müller CW
OpenAccess logo Nat Commun 11 4905 (2020)
PMID: 32999288
Related structures: EMD-10817

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152280 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Transcription factor tau 131 kDa subunit Chain: A
Molecule details ›
Chain: A
Length: 1029 amino acids
Theoretical weight: 120.75 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P33339 (Residues: 1-1025; Coverage: 100%)
Gene names: PCF1, TFC4, YGR047C
Sequence domains:
Transcription factor tau 95 kDa subunit Chain: B
Molecule details ›
Chain: B
Length: 685 amino acids
Theoretical weight: 77.36 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P32367 (Residues: 1-649; Coverage: 100%)
Gene names: TFC1, YBR0919, YBR123C
Sequence domains:
Transcription factor tau 55 kDa subunit Chain: C

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.1Å
Relevant EMDB volumes: EMD-10817
Expression system: Trichoplusia ni

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Citations

4 review citations

Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases.
Girbig et al. (2022)
3 more