6yjp

X-ray diffraction
3.1Å resolution

Crystal structure of a complex between glycosylated NKp30 and its deglycosylated tumour ligand B7-H6

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
PDBe Complex ID:
PDB-CPX-127204 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Natural cytotoxicity triggering receptor 3 ligand 1 Chains: C, D, E
Molecule details ›
Chains: C, D, E
Length: 234 amino acids
Theoretical weight: 26.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q68D85 (Residues: 24-244; Coverage: 51%)
Gene names: B7H6, NCR3LG1
Sequence domains: Immunoglobulin C1-set domain
Natural cytotoxicity triggering receptor 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 13.92 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O14931 (Residues: 19-130; Coverage: 61%)
Gene names: 1C7, LY117, NCR3
Sequence domains: Immunoglobulin V-set domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: C2
Unit cell:
a: 166.044Å b: 86.462Å c: 111.299Å
α: 90° β: 97.58° γ: 90°
R-values:
R R work R free
0.275 0.272 0.322
Expression system: Homo sapiens