› 6yp5

Solution NMR

Solution NMR structure of the oligomerization domain of respiratory syncytial virus phosphoprotein

Released:
DOI: 10.2210/pdb6yp5/pdb
PDB entry 6yp5 coloured by chain, ensemble of 20 models, front view.
PDB entry 6yp5 coloured by chain, ensemble of 20 models, side view.
PDB entry 6yp5 coloured by chain, ensemble of 20 models, top view.
Source organism: Respiratory syncytial virus
Primary publication:
A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein.
Cardone C, Caseau CM, Bardiaux B, Thureaux A, Galloux M, Bajorek M, Eléouët JF, Litaudon M, Bontems F, Sizun C
OpenAccess logo Biomolecules 11 (2021)
PMID: 34439894

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoprotein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 45 amino acids
Theoretical weight: 4.56 KDa
Source organism: Respiratory syncytial virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03421 (Residues: 127-163; Coverage: 15%)
Gene name: P

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 23%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Interactions between the Nucleoprotein and the Phosphoprotein of Pneumoviruses: Structural Insight for Rational Design of Antivirals.
Decool et al. (2021)
1 more

2 mentions without citation

A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein.
Cardone et al. (2021)
1 more

Experimental raw data

Links to raw experimental data available for this entry are listed below

NMR data related to PDB entry 6yp5 available at Biological Magnetic Resonance Data Bank (BMRB)

BMRB accession: BMR34513

Available data:
  • Assigned chemical shifts: 1
  • Spectral peak lists: 1 2 3