› 6yt9

Electron Microscopy
2.7Å resolution

Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit body

Released:
DOI: 10.2210/pdb6yt9/pdb
PDB entry 6yt9 coloured by chain, front view.
PDB entry 6yt9 coloured by chain, side view.
PDB entry 6yt9 coloured by chain, top view.
Source organism: Acinetobacter baumannii
Primary publication:
Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Nicholson D, Edwards TA, O'Neill AJ, Ranson NA
OpenAccess logo Structure 28 1087-1100.e3 (2020)
PMID: 32857965
Related structures: EMD-10914

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111917 (preferred)
Entry contents:
13 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (14 distinct):
Small ribosomal subunit protein uS2 Chain: c
Molecule details ›
Chain: c
Length: 250 amino acids
Theoretical weight: 27.68 KDa
Source organism: Acinetobacter baumannii
UniProt:
  • Canonical: D0CC74 (Residues: 1-250; Coverage: 100%)
Gene names: HMPREF0010_02354, rpsB
Sequence domains: Ribosomal protein S2
Small ribosomal subunit protein uS4 Chain: e
Molecule details ›
Chain: e
Length: 208 amino acids
Theoretical weight: 23.31 KDa
Source organism: Acinetobacter baumannii
UniProt:
  • Canonical: D0CD21 (Residues: 1-208; Coverage: 100%)
Gene names: HMPREF0010_02651, rpsD
Sequence domains:
Small ribosomal subunit protein uS5 Chain: f
Small ribosomal subunit protein bS6 Chain: g
Small ribosomal subunit protein uS8 Chain: i
Small ribosomal subunit protein uS11 Chain: l
Small ribosomal subunit protein uS12 Chain: m
Small ribosomal subunit protein uS15 Chain: p
Small ribosomal subunit protein bS16 Chain: q
Small ribosomal subunit protein uS17 Chain: r
Small ribosomal subunit protein bS18 Chain: s
Small ribosomal subunit protein bS20 Chain: u
Small ribosomal subunit protein bS21 Chain: v
16S ribosomal RNA Chains: 2, 4

Ligands and Environments

1 bound ligand:
Ligand MG 56 x MG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.7Å
Relevant EMDB volumes: EMD-10914

Quick links

Citations

1 review citation

Ribosome-targeting antibiotics and resistance via ribosomal RNA methylation.
Jeremia et al. (2023)
6 other articles

1 mention without citation

Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Nicholson et al. (2020)