Function and Biology Details
Reaction catalysed:
Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-156913 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Histone deacetylase HDA1
Molecule details ›
Chains: A, F
Length: 661 amino acids
Theoretical weight: 74.85 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 661 amino acids
Theoretical weight: 74.85 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical:
P53973 (Residues: 40-700; Coverage: 94%)
Sequence domains:
Histone deacetylase HDA1
Molecule details ›
Chains: B, G
Length: 672 amino acids
Theoretical weight: 76.02 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 672 amino acids
Theoretical weight: 76.02 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P53973 (Residues: 29-700; Coverage: 95%)
Sequence domains:
HDA1 complex subunit 2
HDA1 complex subunit 3
