6z6u

Electron Microscopy
1.25Å resolution

1.25 A structure of human apoferritin obtained from Titan Mono-BCOR microscope

Released:
Source organism: Homo sapiens
Primary publication:
Atomic-resolution protein structure determination by cryo-EM.
Nature 587 157-161 (2020)
PMID: 33087927
Related structures: EMD-11103

Function and Biology Details

Reaction catalysed:
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136244 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin heavy chain Chains: 1, 2, 4, 6, A, B, E, F, G, H, I, K, M, O, P, Q, S, U, W, X, Y, a, e, r
Molecule details ›
Chains: 1, 2, 4, 6, A, B, E, F, G, H, I, K, M, O, P, Q, S, U, W, X, Y, a, e, r
Length: 183 amino acids
Theoretical weight: 21.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02794 (Residues: 1-183; Coverage: 100%)
Gene names: FTH, FTH1, FTHL6, OK/SW-cl.84, PIG15
Sequence domains: Ferritin-like domain

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 1.25Å
Relevant EMDB volumes: EMD-11103
Expression system: Escherichia coli