› 6zer

X-ray diffraction
3.8Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209686 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chains: A, D, E
Molecule details ›
Chains: A, D, E
Length: 203 amino acids
Theoretical weight: 22.76 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 330-532; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
EY6A heavy chain Chains: B, F, H
Molecule details ›
Chains: B, F, H
Length: 226 amino acids
Theoretical weight: 24.35 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
EY6A light chain Chains: C, G, L
Molecule details ›
Chains: C, G, L
Length: 215 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

2 bound ligands:
Ligand NAG 3 x NAG
Ligand PO4 4 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3121
Unit cell:
a: 166.404Å b: 166.404Å c: 270.675Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.212 0.251
Expression systems:
  • Homo sapiens
  • Cricetulus griseus

Quick links

Citations

43 review citations

COVID-19 and Cardiovascular Disease: From Bench to Bedside.
Chung et al. (2021)
42 more

28 mentions without citation

Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies.
Yuan et al. (2021)
27 more