› 6zhi

X-ray diffraction
3.25Å resolution

Structure of the Plasmodium falciparum Hsp70-x substrate binding domain in complex with hydrophobic peptide

Released:
DOI: 10.2210/pdb6zhi/pdb
PDB entry 6zhi coloured by chain, front view.
PDB entry 6zhi coloured by chain, side view.
PDB entry 6zhi coloured by chain, top view.
Source organisms:
Primary publication:
Structure of the PfHsp70-x SBD
Schmidt J, Vakonakis I
To be published

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125615 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Heat shock 70 kDa protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 229 amino acids
Theoretical weight: 25.84 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: K7NTP5 (Residues: 424-650; Coverage: 35%)
Gene name: PF3D7_0831700
Sequence domains: Hsp70 protein
ASN-ARG-LEU-LEU-LEU-THR-GLY Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 7 amino acids
Theoretical weight: 787 Da
Source organism: Plasmodium falciparum
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 71.069Å b: 93.853Å c: 85.296Å
α: 90° β: 99.47° γ: 90°
R-values:
R R work R free
0.298 0.297 0.321
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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