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› 6zr7

X-ray diffraction
1.85Å resolution

X-ray structure of human Dscam Ig7-Ig9

Released:
DOI: 10.2210/pdb6zr7/pdb
Model geometry
Fit model/data
PDB entry 6zr7 coloured by chain, front view.
PDB entry 6zr7 coloured by chain, side view.
PDB entry 6zr7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis.
Kozak S, Bloch Y, De Munck S, Mikula A, Bento I, Savvides SN, Meijers R
OpenAccess logo Acta Crystallogr D Struct Biol 76 1244-1255 (2020)
PMID: 33263330

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-279363 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Cell adhesion molecule DSCAM Chain: AAA
Molecule details ›
Chain: AAA
Length: 308 amino acids
Theoretical weight: 34.25 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O60469 (Residues: 595-884; Coverage: 15%)
Gene name: DSCAM
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, GAL
Carbohydrate polymer
3 bound ligands:
Ligand GOL 1 x GOL
Ligand CA 1 x CA
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: C2
Unit cell:
a: 78.599Å b: 71.421Å c: 92.174Å
α: 90° β: 113.061° γ: 90°
R-values:
R R work R free
0.196 0.195 0.228
Expression system: Homo sapiens

Quick links

Citations

2 review citations

Affecting HEK293 Cell Growth and Production Performance by Modifying the Expression of Specific Genes.
Abaandou et al. (2021)
1 more

1 mention without citation

Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis.
Kozak et al. (2020)