› 6zsy

X-ray diffraction
0.93Å resolution

Crystal structure of the Grindelwald extracellular domain complex

Released:
DOI: 10.2210/pdb6zsy/pdb
PDB entry 6zsy coloured by chain, front view.
PDB entry 6zsy coloured by chain, side view.
PDB entry 6zsy coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions.
Palmerini V, Monzani S, Laurichesse Q, Loudhaief R, Mari S, Cecatiello V, Olieric V, Pasqualato S, Colombani J, Andersen DS, Mapelli M
Nat Commun 12 2070 (2021)
PMID: 33824334

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194268 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein grindelwald Chain: A
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 5.92 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9VJ83 (Residues: 30-81; Coverage: 24%)
Gene names: CG10176, grnd

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P41212
Unit cell:
a: 31.483Å b: 31.483Å c: 97.762Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.13 0.13 0.157
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Regulating metabolism to shape immune function: Lessons from Drosophila.
Bland ML. (2023)
2 more