› 6ztd

X-ray diffraction
3.43Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214308 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Heavy chain of the Fab fragment from BCR derived from the P6540 CLL clone Chain: H
Molecule details ›
Chain: H
Length: 221 amino acids
Theoretical weight: 23.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Light chain of the Fab fragment from BCR derived from the P6540 CLL clone Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.02 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P41
Unit cell:
a: 70.536Å b: 70.536Å c: 106.472Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.217 0.263
Expression system: Homo sapiens

Quick links

Citations

6 review citations

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL.
Agathangelidis et al. (2022)
5 more