› 6zzf

Solution NMR

Structure of the cis-(Tyr39-Pro40) form of the Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1)

Released:
DOI: 10.2210/pdb6zzf/pdb
PDB entry 6zzf coloured by chain, ensemble of 20 models, front view.
PDB entry 6zzf coloured by chain, ensemble of 20 models, side view.
PDB entry 6zzf coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Paramonov AS, Kocharovskaya MV, Tsarev AV, Kulbatskii DS, Loktyushov EV, Shulepko MA, Kirpichnikov MP, Lyukmanova EN, Shenkarev ZO
Int J Mol Sci 21 (2020)
PMID: 33019770

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157145 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Secreted Ly-6/uPAR-related protein 1 Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 8.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P55000 (Residues: 23-103; Coverage: 100%)
Gene names: ARS, SLURP1
Sequence domains: u-PAR/Ly-6 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

α7- and α9-Containing Nicotinic Acetylcholine Receptors in the Functioning of Immune System and in Pain.
Shelukhina et al. (2023)
8 other articles

1 mention without citation

Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Paramonov et al. (2020)