› 7a0h

X-ray diffraction
2.22Å resolution

Structure of homodimeric actin capping protein alpha subunit from Plasmodium berghei

Released:
DOI: 10.2210/pdb7a0h/pdb
PDB entry 7a0h coloured by chain, front view.
PDB entry 7a0h coloured by chain, side view.
PDB entry 7a0h coloured by chain, top view.
Source organism: Plasmodium berghei ANKA
Primary publication:
Structure and function of an atypical homodimeric actin capping protein from the malaria parasite.
Bendes ÁÁ, Kursula P, Kursula I
Cell Mol Life Sci 79 125 (2022)
PMID: 35132495

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105278 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
F-actin-capping protein subunit alpha Chains: A, B
Molecule details ›
Chains: A, B
Length: 294 amino acids
Theoretical weight: 34.13 KDa
Source organism: Plasmodium berghei ANKA
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A509AR49 (Residues: 1-287; Coverage: 94%)
Gene name: PBANKA_1243100
Sequence domains: F-actin capping protein alpha subunit

Ligands and Environments

3 bound ligands:
Ligand BR 25 x BR
Ligand GOL 1 x GOL
Ligand EPE 1 x EPE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 164.49Å b: 35.168Å c: 115.438Å
α: 90° β: 104.437° γ: 90°
R-values:
R R work R free
0.21 0.207 0.257
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

An Atypical F-Actin Capping Protein Modulates Cytoskeleton Behaviors Crucial for Trichomonas vaginalis Colonization.
Wang et al. (2023)