Function and Biology Details
Reactions catalysed:
ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)
ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-207556 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
ATP-dependent translocase ABCB1
Molecule details ›
Chain: A
Length: 1280 amino acids
Theoretical weight: 141.63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 1280 amino acids
Theoretical weight: 141.63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P08183 (Residues: 1-1280; Coverage: 100%)
Sequence domains:
Ig-like domain-containing protein
Molecule details ›
Chain: B
Length: 219 amino acids
Theoretical weight: 24.14 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 219 amino acids
Theoretical weight: 24.14 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
- Canonical: A2NHM3 (Residues: 1-219; Coverage: 100%)
Sequence domains:
