› 7a6u

Electron Microscopy
3.62Å resolution

Cryo-EM structure of the cytoplasmic domain of human TRPC6

Released:
DOI: 10.2210/pdb7a6u/pdb
PDB entry 7a6u coloured by chain, front view.
PDB entry 7a6u coloured by chain, side view.
PDB entry 7a6u coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Grieben M, Pike ACW, Wang D, Mukhopadhyay SMM, Chalk R, Marsden BD, Burgess-Brown NA, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)
Related structures: EMD-11674

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195073 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Short transient receptor potential channel 6 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 957 amino acids
Theoretical weight: 109.78 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9Y210 (Residues: 1-931; Coverage: 100%)
Gene names: TRP6, TRPC6
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand UNX 4 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.62Å
Relevant EMDB volumes: EMD-11674
Expression system: Homo sapiens

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