› 7aaq

X-ray diffraction
1.81Å resolution

sugar/H+ symporter STP10 in outward occluded conformation

Released:
DOI: 10.2210/pdb7aaq/pdb
PDB entry 7aaq coloured by chain, front view.
PDB entry 7aaq coloured by chain, side view.
PDB entry 7aaq coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H+ symporter STP10.
Bavnhøj L, Paulsen PA, Flores-Canales JC, Schiøtt B, Pedersen BP
Nat Plants 7 1409-1419 (2021)
PMID: 34556835

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192311 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sugar transport protein 10 Chain: A
Molecule details ›
Chain: A
Length: 514 amino acids
Theoretical weight: 56.24 KDa
Source organism: Arabidopsis thaliana
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q9LT15 (Residues: 1-514; Coverage: 100%)
Gene names: At3g19940, MPN9.19, STP10
Sequence domains: Sugar (and other) transporter

Ligands and Environments

4 bound ligands:
Ligand BGC 1 x BGC
Ligand OLC 4 x OLC
Ligand XPE 1 x XPE
Ligand ACT 2 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 59.496Å b: 92.78Å c: 119.788Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.187 0.212
Expression system: Saccharomyces cerevisiae

Quick links

Citations

2 review citations

The Tiny Companion Matters: The Important Role of Protons in Active Transports in Plants.
Ku et al. (2022)
1 more

2 mentions without citation

Utilization of AlphaFold2 to Predict MFS Protein Conformations after Selective Mutation.
Xiao et al. (2022)
1 more