Function and Biology Details
Reactions catalysed:
ATP + H(2)O = ADP + phosphate
Peptidylproline (omega=180) = peptidylproline (omega=0)
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero 56-mer (preferred)
Assembly name:
Retention and splicing complex and RNA (preferred)
PDBe Complex ID:
PDB-CPX-129048 (preferred)
Entry contents:
45 distinct polypeptide molecules
4 distinct RNA molecules
4 distinct RNA molecules
Macromolecules (49 distinct):
U5 small nuclear ribonucleoprotein 40 kDa protein
Molecule details ›
Chain: D
Length: 357 amino acids
Theoretical weight: 39.36 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: WD domain, G-beta repeat
Length: 357 amino acids
Theoretical weight: 39.36 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q96DI7 (Residues: 1-357; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Splicing factor 3B subunit 3
Molecule details ›
Chain: E
Length: 1217 amino acids
Theoretical weight: 135.72 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 1217 amino acids
Theoretical weight: 135.72 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: Q15393 (Residues: 1-1217; Coverage: 100%)
Sequence domains:
Small nuclear ribonucleoprotein F
U2 small nuclear ribonucleoprotein A'
Splicing factor 3B subunit 4
Small nuclear ribonucleoprotein G
RNA helicase aquarius
Splicing factor 3B subunit 5
U2 small nuclear ribonucleoprotein B''
Splicing factor 3B subunit 6
Ubiquitin-like protein 5
U5 small nuclear ribonucleoprotein 200 kDa helicase
SNW domain-containing protein 1
BUD13 homolog
Smad nuclear-interacting protein 1
Protein BUD31 homolog
RNA-binding motif protein, X-linked 2
Cell division cycle 5-like protein
Zinc finger matrin-type protein 2
Beta-catenin-like protein 1
116 kDa U5 small nuclear ribonucleoprotein component
Spliceosome-associated protein CWC15 homolog
Serine/arginine repetitive matrix protein 1
DNA/RNA-binding protein KIN17
Pre-mRNA-splicing factor SYF1
Microfibrillar-associated protein 1
Crooked neck-like protein 1
PHD finger-like domain-containing protein 5A
Pleiotropic regulator 1
Small nuclear ribonucleoprotein Sm D2
Peptidyl-prolyl cis-trans isomerase E
RING-type E3 ubiquitin-protein ligase PPIL2
Small nuclear ribonucleoprotein-associated proteins B and B'
Small nuclear ribonucleoprotein Sm D3
Pre-mRNA-processing-splicing factor 8
Pre-mRNA-processing factor 17
Small nuclear ribonucleoprotein E
Pre-mRNA-splicing factor 38A
Small nuclear ribonucleoprotein Sm D1
Pre-mRNA-splicing factor RBM22
Splicing factor 3A subunit 1
Splicing factor 3A subunit 2
Splicing factor 3A subunit 3
Splicing factor 3B subunit 1
Splicing factor 3B subunit 2
