› 7aev

X-ray diffraction
2.77Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159519 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: AAA, CCC
Molecule details ›
Chains: AAA, CCC
Length: 139 amino acids
Theoretical weight: 14.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P69905 (Residues: 3-141; Coverage: 98%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Hemoglobin subunit beta Chains: BBB, DDD
Molecule details ›
Chains: BBB, DDD
Length: 145 amino acids
Theoretical weight: 15.79 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P68871 (Residues: 3-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin

Ligands and Environments

2 bound ligands:
Ligand HEM 4 x HEM
Ligand CMO 4 x CMO
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLAC LCLS BEAMLINE CXI
Spacegroup: P212121
Unit cell:
a: 55.7Å b: 158.1Å c: 67.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.188 0.273

Quick links

Citations

4 review citations

Discerning best practices in XFEL-based biological crystallography - standards for nonstandard experiments.
Gorel et al. (2021)
3 more

2 mentions without citation

Effect of X-ray free-electron laser-induced shockwaves on haemoglobin microcrystals delivered in a liquid jet.
Grünbein et al. (2021)
1 more