7agf

Electron Microscopy
3.1Å resolution

HAd7 knob in complex with 3 EC2-EC3 modules of DSG-2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-147230 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fiber protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 213 amino acids
Theoretical weight: 23.49 KDa
Source organism: Human adenovirus 7
Expression system: Escherichia coli
UniProt:
  • Canonical: P15141 (Residues: 135-343; Coverage: 61%)
Gene name: L5
Sequence domains: Adenoviral fibre protein (knob domain)
Desmoglein-2 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 243 amino acids
Theoretical weight: 27.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q14126 (Residues: 149-386; Coverage: 22%)
Gene names: CDHF5, DSG2
Sequence domains: Cadherin domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-11778
Expression systems:
  • Escherichia coli
  • Homo sapiens