› 7agy

X-ray diffraction
1.54Å resolution

Structure of the N-domain of the K+/H+ antiporter subunit KhtT at pH 8.5

Released:
DOI: 10.2210/pdb7agy/pdb
PDB entry 7agy coloured by chain, front view.
PDB entry 7agy coloured by chain, side view.
PDB entry 7agy coloured by chain, top view.
Source organism: Bacillus subtilis subsp. subtilis str. 168
Primary publication:
c-di-AMP, a likely master regulator of bacterial K+ homeostasis machinery, activates a K+ exporter.
Cereija TB, Guerra JPL, Jorge JMP, Morais-Cabral JH
Proc Natl Acad Sci U S A 118 (2021)
PMID: 33790011

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126592 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
K(+)/H(+) antiporter subunit KhtT Chains: A, B
Molecule details ›
Chains: A, B
Length: 71 amino acids
Theoretical weight: 8.01 KDa
Source organism: Bacillus subtilis subsp. subtilis str. 168
Expression system: Escherichia coli
UniProt:
  • Canonical: O07535 (Residues: 2-68; Coverage: 41%)
Gene names: BSU09860, khtT, yhaT

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 35.197Å b: 63.594Å c: 64.568Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.234
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The role of bacterial cyclic di-adenosine monophosphate in the host immune response.
Cheng et al. (2022)
3 more

1 mention without citation

c-di-AMP, a likely master regulator of bacterial K+ homeostasis machinery, activates a K+ exporter.
Cereija et al. (2021)