› 7aoi

Electron Microscopy
3.5Å resolution

Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate

Released:
DOI: 10.2210/pdb7aoi/pdb
PDB entry 7aoi coloured by chain, front view.
PDB entry 7aoi coloured by chain, side view.
PDB entry 7aoi coloured by chain, top view.
Source organism: Trypanosoma brucei
Primary publication:
Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Tobiasson V, Gahura O, Aibara S, Baradaran R, Zíková A, Amunts A
EMBO J 40 e106292 (2021)
PMID: 33576519
Related structures: EMD-11845

Function and Biology Details

Reactions catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
UTP + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 83-mer (preferred)
PDBe Complex ID:
PDB-CPX-104888 (preferred)
Entry contents:
81 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (82 distinct):
39S ribosomal protein L28 Chain: A1
Molecule details ›
Chain: A1
Length: 217 amino acids
Theoretical weight: 25.44 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L6A9 (Residues: 10-226; Coverage: 90%)
Gene name: DPX39_060044700
Large ribosomal subunit protein uL29m Chain: A2
Molecule details ›
Chain: A2
Length: 463 amino acids
Theoretical weight: 53.07 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q38EM7 (Residues: 9-471; Coverage: 98%)
Gene name: Tb09.160.5240
Sequence domains: Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
Ribosomal protein L30p/L7e Chain: A3
Molecule details ›
Chain: A3
Length: 150 amino acids
Theoretical weight: 17.51 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L456 (Residues: 51-200; Coverage: 69%)
Gene name: DPX39_090043700
bL32m Chain: A5
Molecule details ›
Chain: A5
Length: 55 amino acids
Theoretical weight: 6.93 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LD92 (Residues: 26-80; Coverage: 69%)
Gene name: DPX39_040026300
bL33m Chain: A8
Molecule details ›
Chain: A8
Length: 142 amino acids
Theoretical weight: 17.17 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L070 (Residues: 40-181; Coverage: 79%)
Gene name: DPX39_100023700
Ribosomal protein L3 mitochondrial, putative Chain: AE
Molecule details ›
Chain: AE
Length: 367 amino acids
Theoretical weight: 42.54 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q580R4 (Residues: 38-404; Coverage: 78%)
Gene names: Tb03.5L5.850, Tb927.3.5610
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4m Chain: AF
Molecule details ›
Chain: AF
Length: 442 amino acids
Theoretical weight: 51.18 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KTM7 (Residues: 18-459; Coverage: 96%)
Gene names: DPX39_000044600, MRPL4
Sequence domains: Ribosomal protein L4/L1 family
Ribosomal protein L9 domain-containing protein Chain: AI
Molecule details ›
Chain: AI
Length: 212 amino acids
Theoretical weight: 25.39 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L8Y1 (Residues: 9-220; Coverage: 81%)
Gene name: DPX39_050040600
Sequence domains: Ribosomal protein L9, N-terminal domain
Large ribosomal subunit protein uL11m Chain: AK
Molecule details ›
Chain: AK
Length: 278 amino acids
Theoretical weight: 29.59 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LEQ0 (Residues: 26-236; Coverage: 62%)
Gene names: DPX39_020019500, DPX39_020020500
Sequence domains:
50S ribosomal protein L13 Chain: AN
Molecule details ›
Chain: AN
Length: 171 amino acids
Theoretical weight: 20.33 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LAE5 (Residues: 10-180; Coverage: 85%)
Gene name: DPX39_040013100
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL15/eL18 domain-containing protein Chain: AP
Molecule details ›
Chain: AP
Length: 354 amino acids
Theoretical weight: 41.64 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L758 (Residues: 10-363; Coverage: 95%)
Gene name: DPX39_050046600
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
50S ribosomal protein L17 Chain: AR
Molecule details ›
Chain: AR
Length: 256 amino acids
Theoretical weight: 30.48 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LAG5 (Residues: 11-266; Coverage: 85%)
Gene name: DPX39_040059200
Sequence domains: Ribosomal protein L17
bL19m Chain: AT
Molecule details ›
Chain: AT
Length: 138 amino acids
Theoretical weight: 16.15 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LD66 (Residues: 2-139; Coverage: 96%)
Gene name: DPX39_010015500
Large ribosomal subunit protein bL20c Chain: AU
Molecule details ›
Chain: AU
Length: 196 amino acids
Theoretical weight: 22.38 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KV21 (Residues: 10-205; Coverage: 92%)
Gene name: DPX39_110073300
Large ribosomal subunit protein bL21m Chain: AV
Molecule details ›
Chain: AV
Length: 180 amino acids
Theoretical weight: 20.18 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LA68 (Residues: 6-185; Coverage: 96%)
Gene name: DPX39_070051600
Sequence domains: Ribosomal prokaryotic L21 protein
Large ribosomal subunit protein uL22c Chain: AW
Molecule details ›
Chain: AW
Length: 277 amino acids
Theoretical weight: 31.95 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L4Z4 (Residues: 2-278; Coverage: 100%)
Gene name: DPX39_070036200
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein uL23m Chain: AX
Molecule details ›
Chain: AX
Length: 165 amino acids
Theoretical weight: 19.69 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KW11 (Residues: 64-228; Coverage: 67%)
Gene name: DPX39_110013100
KOW domain-containing protein Chain: AY
Molecule details ›
Chain: AY
Length: 340 amino acids
Theoretical weight: 39.72 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: C9ZK52 (Residues: 1-340; Coverage: 90%)
Gene name: TbgDal_III1550
mL41 Chain: Ae
Molecule details ›
Chain: Ae
Length: 116 amino acids
Theoretical weight: 13.15 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KTI0 (Residues: 47-162; Coverage: 59%)
Gene name: DPX39_110069600
mL42 Chain: Af
Molecule details ›
Chain: Af
Length: 133 amino acids
Theoretical weight: 15.19 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KXE9 (Residues: 41-173; Coverage: 70%)
Gene name: DPX39_110072400
Large ribosomal subunit protein mL43 Chain: Ag
Molecule details ›
Chain: Ag
Length: 185 amino acids
Theoretical weight: 22.11 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LCE5 (Residues: 2-186; Coverage: 71%)
Gene name: DPX39_040076300
Sequence domains: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
mL49 Chain: Al
Molecule details ›
Chain: Al
Length: 182 amino acids
Theoretical weight: 20.51 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L7H5 (Residues: 37-218; Coverage: 84%)
Gene name: DPX39_050037600
mL52 Chain: Ao
Molecule details ›
Chain: Ao
Length: 133 amino acids
Theoretical weight: 14.98 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KS48 (Residues: 1281-1413; Coverage: 9%)
Gene name: DPX39_000058300
mL53 Chain: Ap
Molecule details ›
Chain: Ap
Length: 288 amino acids
Theoretical weight: 33.28 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L3K9 (Residues: 15-302; Coverage: 93%)
Gene names: DPX39_070039500, DPX39_070040000
T. brucei spp.-specific protein Chain: At
Molecule details ›
Chain: At
Length: 145 amino acids
Theoretical weight: 17.1 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: C9ZU82 (Residues: 51-195; Coverage: 74%)
Gene name: TbgDal_VII8230
mL64,mL64 Chain: Av
Molecule details ›
Chain: Av
Length: 197 amino acids
Theoretical weight: 23.72 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KTC7 (Residues: 27-222; Coverage: 81%)
Gene name: DPX39_110093700
Mitochondrial RNA binding protein Chain: BA
Molecule details ›
Chain: BA
Length: 798 amino acids
Theoretical weight: 89.79 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: D0A5V6 (Residues: 27-824; Coverage: 96%)
Gene name: TbgDal_XI1730
mL68,mL68,mL68 Chain: BB
Molecule details ›
Chain: BB
Length: 371 amino acids
Theoretical weight: 40.6 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KX69 (Residues: 62-450; Coverage: 69%)
Gene name: DPX39_100011000
mL70 Chain: BD
Molecule details ›
Chain: BD
Length: 417 amino acids
Theoretical weight: 47.56 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L6S3 (Residues: 2-418; Coverage: 94%)
Gene name: DPX39_060046200
mL71 Chain: BE
Molecule details ›
Chain: BE
Length: 438 amino acids
Theoretical weight: 49.03 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: C9ZSQ8 (Residues: 11-448; Coverage: 98%)
Gene name: TbgDal_VII3790
Tetratricopeptide repeat Chain: BF
Molecule details ›
Chain: BF
Length: 421 amino acids
Theoretical weight: 48.74 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LA84 (Residues: 1-421; Coverage: 99%)
Gene name: DPX39_060043600
mL74 Chain: BH
Molecule details ›
Chain: BH
Length: 225 amino acids
Theoretical weight: 25.89 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KXN2 (Residues: 89-313; Coverage: 65%)
Gene name: DPX39_100080100
Mitochondrial RNA binding complex 1 subunit Chain: BI
Molecule details ›
Chain: BI
Length: 323 amino acids
Theoretical weight: 37.5 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KZH2 (Residues: 20-342; Coverage: 94%)
Gene names: DPX39_100008800, PPR5
mL76 Chain: BJ
Molecule details ›
Chain: BJ
Length: 161 amino acids
Theoretical weight: 18.93 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KX00 (Residues: 173-333; Coverage: 48%)
Gene name: DPX39_110080800
J domain-containing protein Chain: BK
Molecule details ›
Chain: BK
Length: 273 amino acids
Theoretical weight: 30.69 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: C9ZQR6 (Residues: 84-386; Coverage: 71%)
Gene name: TbgDal_VI2240
Sequence domains: DnaJ domain
mL78 Chain: BL
Molecule details ›
Chain: BL
Length: 276 amino acids
Theoretical weight: 31.32 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L166 (Residues: 31-306; Coverage: 88%)
Gene name: DPX39_100117000
mL80 Chain: BN
Molecule details ›
Chain: BN
Length: 214 amino acids
Theoretical weight: 25.44 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: C9ZQF0 (Residues: 53-266; Coverage: 71%)
Gene name: TbgDal_VI1080
mL81 Chain: BO
Molecule details ›
Chain: BO
Length: 227 amino acids
Theoretical weight: 25.45 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KS29 (Residues: 36-262; Coverage: 87%)
Gene name: DPX39_000049400
Peptidyl-prolyl cis-trans isomerase Chain: BQ
Molecule details ›
Chain: BQ
Length: 185 amino acids
Theoretical weight: 20.29 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q57WF8 (Residues: 16-200; Coverage: 80%)
Gene names: Tb07.28B13.640, Tb927.7.3430
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
mL84 Chain: BR
Molecule details ›
Chain: BR
Length: 195 amino acids
Theoretical weight: 23.42 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L538 (Residues: 11-205; Coverage: 95%)
Gene name: DPX39_060045100
mL85 Chain: BS
Molecule details ›
Chain: BS
Length: 144 amino acids
Theoretical weight: 16.96 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q38FG8 (Residues: 20-163; Coverage: 73%)
Gene name: Tb09.160.2250
mL86 Chain: BT
Molecule details ›
Chain: BT
Length: 167 amino acids
Theoretical weight: 19.67 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L8W0 (Residues: 10-176; Coverage: 87%)
Gene name: DPX39_050048100
mL87 Chain: BU
Molecule details ›
Chain: BU
Length: 82 amino acids
Theoretical weight: 9.89 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KX50 (Residues: 104-185; Coverage: 44%)
Gene name: DPX39_110051000
mL89 Chain: BW
Molecule details ›
Chain: BW
Length: 187 amino acids
Theoretical weight: 22.08 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q57WW5 (Residues: 2-188; Coverage: 100%)
Gene names: Tb03.27F10.650, Tb927.3.820
LIM zinc-binding domain-containing protein Chain: BX
Molecule details ›
Chain: BX
Length: 116 amino acids
Theoretical weight: 13.19 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L637 (Residues: 61-174; Coverage: 60%)
Gene name: DPX39_060020200
Sequence domains: LIM domain
Peptidyl-prolyl cis-trans isomerase Chain: BZ
Molecule details ›
Chain: BZ
Length: 189 amino acids
Theoretical weight: 20.41 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KTB1 (Residues: 2-190; Coverage: 100%)
Gene names: DPX39_110065100, PPIase
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
mL93 Chain: Ba
Molecule details ›
Chain: Ba
Length: 135 amino acids
Theoretical weight: 16.88 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: D0A4T0 (Residues: 19-153; Coverage: 88%)
Gene name: TbgDal_X13710
Rhodanese-like domain containing protein Chain: Bb
Molecule details ›
Chain: Bb
Length: 103 amino acids
Theoretical weight: 11.45 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L3K4 (Residues: 38-140; Coverage: 64%)
Gene name: DPX39_090034500
mL95 Chain: Bc
Molecule details ›
Chain: Bc
Length: 137 amino acids
Theoretical weight: 16.81 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L276 (Residues: 10-146; Coverage: 94%)
Gene name: DPX39_100120200
mL98 Chain: Bf
Molecule details ›
Chain: Bf
Length: 86 amino acids
Theoretical weight: 10.1 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L4A5 (Residues: 27-112; Coverage: 76%)
Gene name: DPX39_100143900
mL99 Chain: Bg
Molecule details ›
Chain: Bg
Length: 82 amino acids
Theoretical weight: 9.31 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LDF0 (Residues: 24-105; Coverage: 78%)
Gene name: DPX39_020008800
mL100,mL100 Chain: Bh
Molecule details ›
Chain: Bh
Length: 92 amino acids
Theoretical weight: 10.55 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L2V1 (Residues: 2-92; Coverage: 99%)
Gene name: DPX39_090047800
UNK1 Chain: UA
Molecule details ›
Chain: UA
Length: 46 amino acids
Theoretical weight: 3.29 KDa
Source organism: Trypanosoma brucei
UNK2 Chain: UB
Molecule details ›
Chain: UB
Length: 9 amino acids
Theoretical weight: 658 Da
Source organism: Trypanosoma brucei
UNK3 Chain: UC
Molecule details ›
Chain: UC
Length: 14 amino acids
Theoretical weight: 1.01 KDa
Source organism: Trypanosoma brucei
UNK4 Chain: UD
Molecule details ›
Chain: UD
Length: 8 amino acids
Theoretical weight: 587 Da
Source organism: Trypanosoma brucei
UNK5 Chain: UE
Molecule details ›
Chain: UE
Length: 12 amino acids
Theoretical weight: 871 Da
Source organism: Trypanosoma brucei
UNK6/mt-LAF15_2 Chain: UF
Molecule details ›
Chain: UF
Length: 139 amino acids
Theoretical weight: 9.9 KDa
Source organism: Trypanosoma brucei
UNK7 Chain: UG
Molecule details ›
Chain: UG
Length: 19 amino acids
Theoretical weight: 1.37 KDa
Source organism: Trypanosoma brucei
UNK8 Chain: UH
Molecule details ›
Chain: UH
Length: 17 amino acids
Theoretical weight: 1.23 KDa
Source organism: Trypanosoma brucei
UNK9 Chain: UI
Molecule details ›
Chain: UI
Length: 39 amino acids
Theoretical weight: 2.79 KDa
Source organism: Trypanosoma brucei
UNK10 Chain: UJ
Molecule details ›
Chain: UJ
Length: 25 amino acids
Theoretical weight: 1.79 KDa
Source organism: Trypanosoma brucei
UNK11 Chain: UK
Molecule details ›
Chain: UK
Length: 47 amino acids
Theoretical weight: 3.36 KDa
Source organism: Trypanosoma brucei
mt-LAF7,mt-LAF7 Chain: XA
Molecule details ›
Chain: XA
Length: 155 amino acids
Theoretical weight: 18.5 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q387S8 (Residues: 3-156; Coverage: 99%)
Gene name: Tb10.61.0430
DEAD-box helicase, putative Chain: XB
Molecule details ›
Chain: XB
Length: 668 amino acids
Theoretical weight: 76.35 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: D0A9G9 (Residues: 47-712; Coverage: 88%)
Gene name: TbgDal_XI14390
Sequence domains:
TRUD domain-containing protein Chain: XC
Molecule details ›
Chain: XC
Length: 616 amino acids
Theoretical weight: 69.43 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: D0A7A5 (Residues: 11-626; Coverage: 98%)
Gene name: TbgDal_XI6740
Acyl carrier protein Chains: XD, XE
Molecule details ›
Chains: XD, XE
Length: 83 amino acids
Theoretical weight: 9.78 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q57WW9 (Residues: 64-146; Coverage: 56%)
Gene names: Tb03.27F10.580, Tb927.3.860
Sequence domains: Phosphopantetheine attachment site
mt-LAF15_1 Chain: XF
Molecule details ›
Chain: XF
Length: 198 amino acids
Theoretical weight: 21.69 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LB16 (Residues: 120-317; Coverage: 62%)
Gene name: DPX39_040076400
50S ribosomal protein L14 Chain: XG
Molecule details ›
Chain: XG
Length: 170 amino acids
Theoretical weight: 19.56 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6LE16 (Residues: 20-189; Coverage: 90%)
Gene name: DPX39_040011700
Sequence domains: Ribosomal protein L14p/L23e
mt-LAF8 Chain: XH
Molecule details ›
Chain: XH
Length: 533 amino acids
Theoretical weight: 58.95 KDa
Source organism: Trypanosoma brucei
mt-LAF14 Chain: XI
Molecule details ›
Chain: XI
Length: 703 amino acids
Theoretical weight: 78.94 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q57U79 (Residues: 25-727; Coverage: 96%)
Gene names: Tb05.6E7.850, Tb927.5.3870
Oligomerization domain containing protein Chain: XJ
Molecule details ›
Chain: XJ
Length: 150 amino acids
Theoretical weight: 17.34 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L766 (Residues: 163-312; Coverage: 43%)
Gene name: DPX39_060038300
Sequence domains: Ribosomal silencing factor during starvation
GTP-binding protein, putative Chain: XL
Molecule details ›
Chain: XL
Length: 528 amino acids
Theoretical weight: 60.25 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: C9ZS56 (Residues: 45-570; Coverage: 96%)
Gene name: TbgDal_VII1650
Sequence domains:
Complex1-LYR-like Chain: XM
Molecule details ›
Chain: XM
Length: 91 amino acids
Theoretical weight: 10.61 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L7X4 (Residues: 25-115; Coverage: 78%)
Gene name: DPX39_070052300
mt-LAF12 Chain: XN
Molecule details ›
Chain: XN
Length: 620 amino acids
Theoretical weight: 70.34 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q57YY3 (Residues: 49-668; Coverage: 90%)
Gene names: Tb08.28L1.320, Tb927.8.3300
tRNA/rRNA methyltransferase SpoU type domain-containing protein Chain: XO
Molecule details ›
Chain: XO
Length: 428 amino acids
Theoretical weight: 48.53 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L241 (Residues: 78-505; Coverage: 76%)
Gene name: DPX39_090076800
Sequence domains: SpoU rRNA Methylase family
Pseudouridine synthase RsuA/RluA-like domain-containing protein Chain: XP
Molecule details ›
Chain: XP
Length: 371 amino acids
Theoretical weight: 42.58 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q38FJ3 (Residues: 35-405; Coverage: 91%)
Gene name: Tb09.160.2000
Sequence domains: RNA pseudouridylate synthase
G domain-containing protein Chain: XQ
Molecule details ›
Chain: XQ
Length: 305 amino acids
Theoretical weight: 33.91 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L0D5 (Residues: 34-338; Coverage: 68%)
Gene name: DPX39_090049700
Sequence domains: 50S ribosome-binding GTPase
Fungal lipase-like domain-containing protein Chain: XR
Molecule details ›
Chain: XR
Length: 161 amino acids
Theoretical weight: 18.81 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6L1Y4 (Residues: 3-163; Coverage: 31%)
Gene name: DPX39_090084400
mL101 Chain: XS
Molecule details ›
Chain: XS
Length: 182 amino acids
Theoretical weight: 21.8 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: Q4GZ80 (Residues: 22-203; Coverage: 74%)
Gene name: TB927.1.1390
mt-LAF19 Chain: XT
Molecule details ›
Chain: XT
Length: 97 amino acids
Theoretical weight: 11.41 KDa
Source organism: Trypanosoma brucei
UniProt:
  • Canonical: A0A3L6KWY9 (Residues: 6-102; Coverage: 95%)
Gene name: DPX39_110072000
mt-LSU rRNA Chain: AA
Molecule details ›
Chain: AA
Length: 758 nucleotides
Theoretical weight: 242.54 KDa
Sequence domains: Trypanosomatid mitochondrial large subunit ribosomal RNA

Ligands and Environments

6 bound ligands:
Ligand FES 1 x FES
Ligand NAD 1 x NAD
Ligand ZN 4 x ZN
Ligand MG 1 x MG
Ligand ADP 1 x ADP
Ligand GTP 2 x GTP
1 modified residue:
Ligand 4HH 2 x 4HH

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-11845

Quick links

Citations

2 review citations

The Diseased Mitoribosome.
Ferrari et al. (2021)
1 more