› 7b6e

Electron Microscopy
4.5Å resolution

Drosophila melanogaster TRAPP C8 subunits region 355 to 661

Released:
DOI: 10.2210/pdb7b6e/pdb
PDB entry 7b6e coloured by chain, front view.
PDB entry 7b6e coloured by chain, side view.
PDB entry 7b6e coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Galindo A, Planelles-Herrero VJ, Degliesposti G, Munro S
EMBO J 40 e107608 (2021)
PMID: 34018214
Related structures: EMD-12053

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194319 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FI18195p1 Chain: A
Molecule details ›
Chain: A
Length: 307 amino acids
Theoretical weight: 35.41 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9VW22 (Residues: 355-661; Coverage: 23%)
Gene names: CG8793, Dmel\CG8793, Dmel_CG8793, TRAPPC8, l(3)76BDm, l(3)76BDm-RA, l(3)L3809
Sequence domains: ER-Golgi trafficking TRAPP I complex 85 kDa subunit

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-12053
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017

Quick links

Citations

4 review citations

Who's in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond.
Borchers et al. (2021)
3 more

1 mention without citation

Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Galindo et al. (2021)