› 7bbz

X-ray diffraction
1.77Å resolution

Crystal structure of apo aldo-keto reductase from Agrobacterium tumefaciens

Released:
DOI: 10.2210/pdb7bbz/pdb
PDB entry 7bbz coloured by chain, front view.
PDB entry 7bbz coloured by chain, side view.
PDB entry 7bbz coloured by chain, top view.
Source organism: Agrobacterium fabrum str. C58
Primary publication:
Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria.
Sharma M, Lingford JP, Petricevic M, Snow AJD, Zhang Y, Järvå MA, Mui JW, Scott NE, Saunders EC, Mao R, Epa R, da Silva BM, Pires DEV, Ascher DB, McConville MJ, Davies GJ, Williams SJ, Goddard-Borger ED
Proc Natl Acad Sci U S A 119 (2022)
PMID: 35074914

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108847 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-dehydroglucose reductase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 319 amino acids
Theoretical weight: 34.33 KDa
Source organism: Agrobacterium fabrum str. C58
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A9CEY6 (Residues: 1-297; Coverage: 100%)
Gene names: Atu3278, smoB
Sequence domains: Aldo/keto reductase family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2221
Unit cell:
a: 89.341Å b: 137.547Å c: 153.843Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.209
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies.
Lin et al. (2023)
1 more

1 mention without citation

Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria.
Sharma et al. (2022)