› 7bne

X-ray diffraction
1.7Å resolution

Notum Nicotine

Released:
DOI: 10.2210/pdb7bne/pdb
PDB entry 7bne coloured by chain, front view.
PDB entry 7bne coloured by chain, side view.
PDB entry 7bne coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhao Y, Jones EY

Function and Biology Details

Reaction catalysed: 
[Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine + H(2)O = [Wnt]-L-serine + (9Z)-hexadec-9-enoate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180133 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Palmitoleoyl-protein carboxylesterase NOTUM Chain: A
Molecule details ›
Chain: A
Length: 383 amino acids
Theoretical weight: 43.57 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6P988 (Residues: 81-451; Coverage: 78%)
Gene names: NOTUM, OK/SW-CL.30
Sequence domains: Pectinacetylesterase

Ligands and Environments

4 bound ligands:
Ligand GOL 2 x GOL
Ligand SO4 2 x SO4
Ligand NAG 1 x NAG
Ligand NCT 1 x NCT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 60.29Å b: 71.69Å c: 78.17Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.197
Expression system: Homo sapiens

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