7bxu

Electron Microscopy
3.7Å resolution

CLC-7/Ostm1 membrane protein complex

Released:
Source organism: Homo sapiens
Primary publication:
Molecular insights into the human CLC-7/Ostm1 transporter.
Sci Adv 6 eabb4747 (2020)
PMID: 32851177
Related structures: EMD-30238

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-156418 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Osteopetrosis-associated transmembrane protein 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 334 amino acids
Theoretical weight: 37.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q86WC4 (Residues: 1-334; Coverage: 100%)
Gene names: GL, HSPC019, OSTM1, UNQ6098/PRO21201
Sequence domains: Osteopetrosis-associated transmembrane protein 1 precursor
H(+)/Cl(-) exchange transporter 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 805 amino acids
Theoretical weight: 88.77 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P51798 (Residues: 1-805; Coverage: 100%)
Gene name: CLCN7
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-30238
Expression system: Homo sapiens