› 7bxv

X-ray diffraction
1.75Å resolution

11A1 antibody-peptide complex

Released:
DOI: 10.2210/pdb7bxv/pdb
Model geometry
Fit model/data
PDB entry 7bxv coloured by chain, front view.
PDB entry 7bxv coloured by chain, side view.
PDB entry 7bxv coloured by chain, top view.
Source organisms:
Primary publication:
APOE epsilon 4 allele advances the age-dependent decline of amyloid beta clearance in the human cortex.
Saito A, Kageyama Y, Pletnikova O, Rudow GL, An Y, Irie Y, Kita A, Miki K, Li L, Southall P, Irie K, Troncoso JC
Biorxiv (2022)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-211788 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fab of the 11A1 antibody L chain Chain: L
Molecule details ›
Chain: L
Length: 217 amino acids
Theoretical weight: 23.87 KDa
Source organism: Mus musculus
Fab of the 11A1 antibody H chain Chain: H
Molecule details ›
Chain: H
Length: 218 amino acids
Theoretical weight: 23.77 KDa
Source organism: Mus musculus
TYR-GLU-VAL-HIS-HIS Chain: A

Ligands and Environments

1 bound ligand:
Ligand EDO 5 x EDO
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P21
Unit cell:
a: 40.639Å b: 123.774Å c: 45.692Å
α: 90° β: 99.743° γ: 90°
R-values:
R R work R free
0.167 0.166 0.194
Expression system: Not provided

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