7byd

X-ray diffraction
2.8Å resolution

Crystal structure of SN45 TCR in complex with lipopeptide-bound Mamu-B*05104

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-207651 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Ig-like domain-containing protein Chains: A, F
Molecule details ›
Chains: A, F
Length: 276 amino acids
Theoretical weight: 31.92 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: B2ZHY7 (Residues: 22-297; Coverage: 82%)
Gene names: B, Mamu-B
Sequence domains:
Beta-2-microglobulin Chains: B, G
Molecule details ›
Chains: B, G
Length: 100 amino acids
Theoretical weight: 11.73 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6V7J5 (Residues: 20-119; Coverage: 100%)
Gene name: B2M
Sequence domains: Immunoglobulin C1-set domain
GLY-GLY-ALA-ILE Chains: C, H
Molecule details ›
Chains: C, H
Length: 4 amino acids
Theoretical weight: 316 Da
Source organism: Simian immunodeficiency virus
Expression system: Not provided
SN45 T cell receptor alpha chain Chains: D, I
Molecule details ›
Chains: D, I
Length: 198 amino acids
Theoretical weight: 21.81 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
SN45 T cell receptor beta chain Chains: E, J
Molecule details ›
Chains: E, J
Length: 245 amino acids
Theoretical weight: 28.09 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P21
Unit cell:
a: 83.937Å b: 95.071Å c: 123.352Å
α: 90° β: 90.894° γ: 90°
R-values:
R R work R free
0.188 0.185 0.25
Expression systems:
  • Escherichia coli
  • Not provided