› 7c3q

X-ray diffraction
1.8Å resolution

Human MdmX protein in complex with Nutlin3a

Released:
DOI: 10.2210/pdb7c3q/pdb
PDB entry 7c3q coloured by chain, front view.
PDB entry 7c3q coloured by chain, side view.
PDB entry 7c3q coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Su ZD, Cheng XY, Zhang BL, Kuang ZK, Yang J, Li ZC, Yu JP, Zhao ZT, Cao CZ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127312 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein Mdm4 Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 11.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: O15151 (Residues: 23-108; Coverage: 18%)
Gene names: MDM4, MDMX

Ligands and Environments

3 bound ligands:
Ligand O4B 1 x O4B
Ligand NUT 1 x NUT
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P43212
Unit cell:
a: 47.727Å b: 47.727Å c: 92.321Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.241
Expression system: Escherichia coli K-12

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