› 7c62

X-ray diffraction
2.03Å resolution

The Crystal Structure of Parkinson disease protein 7 (DJ-1) from Biortus

Released:
DOI: 10.2210/pdb7c62/pdb
PDB entry 7c62 coloured by chain, front view.
PDB entry 7c62 coloured by chain, side view.
PDB entry 7c62 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang F, Lin D, Lv Z, Tan J

Function and Biology Details

Reaction catalysed: 
An N(6)-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H(2)O = a [protein]-L-lysine + lactate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189205 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Parkinson disease protein 7 Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 21.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99497 (Residues: 1-189; Coverage: 100%)
Gene name: PARK7
Sequence domains: DJ-1/PfpI family

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P3121
Unit cell:
a: 74.57Å b: 74.57Å c: 74.956Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.153 0.152 0.174
Expression system: Escherichia coli

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