› 7cfx

X-ray diffraction
2.5Å resolution

Function and Biology Details

Reaction catalysed: 
A primary alcohol + 2 cytochrome c(L) = an aldehyde + 2 reduced cytochrome c(L) + 2 H(+)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178835 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Methanol dehydrogenase protein, large subunit Chains: A, B, C, D, G, H, M, N
Molecule details ›
Chains: A, B, C, D, G, H, M, N
Length: 573 amino acids
Theoretical weight: 63.69 KDa
Source organism: Methylococcus capsulatus str. Bath
UniProt:
  • Canonical: Q60AR6 (Residues: 29-601; Coverage: 99%)
Gene names: MCA0779, mxaF
Sequence domains:
Methanol dehydrogenase [cytochrome c] subunit 2 Chains: E, F, I, J, K, L, O, P
Molecule details ›
Chains: E, F, I, J, K, L, O, P
Length: 72 amino acids
Theoretical weight: 8.23 KDa
Source organism: Methylococcus capsulatus str. Bath
UniProt:
  • Canonical: Q60AR3 (Residues: 23-94; Coverage: 100%)
Gene names: MCA0782, mxaI
Sequence domains: Methanol dehydrogenase beta subunit

Ligands and Environments


Cofactor: Ligand PQQ 8 x PQQ
1 bound ligand:
Ligand CA 8 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL15A1
Spacegroup: P212121
Unit cell:
a: 127.901Å b: 211.028Å c: 221.723Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.18 0.24

Quick links

Citations

1 review citation

Pyrroloquinoline-Quinone Is More Than an Antioxidant: A Vitamin-like Accessory Factor Important in Health and Disease Prevention.
Jonscher et al. (2021)
4 other articles