› 7cg3

Electron Microscopy
5.1Å resolution

Staggered ring conformation of CtHsp104 (Hsp104 from Chaetomium Thermophilum)

Released:
DOI: 10.2210/pdb7cg3/pdb
PDB entry 7cg3 coloured by chain, front view.
PDB entry 7cg3 coloured by chain, side view.
PDB entry 7cg3 coloured by chain, top view.
Source organism: Chaetomium thermophilum
Primary publication:
Split conformation of Chaetomium thermophilum Hsp104 disaggregase.
Inoue Y, Hanazono Y, Noi K, Kawamoto A, Kimatsuka M, Harada R, Takeda K, Kita R, Iwamasa N, Shibata K, Noguchi K, Shigeta Y, Namba K, Ogura T, Miki K, Shinohara K, Yohda M
Structure 29 721-730.e6 (2021)
PMID: 33651974
Related structures: EMD-30349

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Clp R domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 764 amino acids
Theoretical weight: 85.06 KDa
Source organism: Chaetomium thermophilum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A2Z6G185 (Residues: 164-926; Coverage: 82%)
Gene name: hsp104
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.1Å
Relevant EMDB volumes: EMD-30349
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Resisting the Heat: Bacterial Disaggregases Rescue Cells From Devastating Protein Aggregation.
Katikaridis et al. (2021)