› 7cuo

X-ray diffraction
2Å resolution

IclR transcription factor complexed with 4-hydroxybenzoic acid from Microbacterium hydrocarbonoxydans

Released:
DOI: 10.2210/pdb7cuo/pdb
PDB entry 7cuo coloured by chain, front view.
PDB entry 7cuo coloured by chain, side view.
PDB entry 7cuo coloured by chain, top view.
Source organism: Microbacterium hydrocarbonoxydans
Primary publication:
Structural basis of the conformational changes in Microbacterium hydrocarbonoxydans IclR transcription factor homolog due to ligand binding.
Akiyama T, Sasaki Y, Ito S, Yajima S
Biochim Biophys Acta Proteins Proteom 1869 140644 (2021)
PMID: 33716191

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168131 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 270 amino acids
Theoretical weight: 29.32 KDa
Source organism: Microbacterium hydrocarbonoxydans
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

2 bound ligands:
Ligand SO4 8 x SO4
Ligand PHB 2 x PHB
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P41212
Unit cell:
a: 83.08Å b: 83.08Å c: 203.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.202 0.218
Expression system: Escherichia coli BL21(DE3)

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