Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-211102 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Prostaglandin E2 receptor EP4 subtype
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 36.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: 7 transmembrane receptor (rhodopsin family)
Length: 333 amino acids
Theoretical weight: 36.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P35408 (Residues: 4-366; Coverage: 66%)
Sequence domains: 7 transmembrane receptor (rhodopsin family)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Molecule details ›
Chain: B
Length: 345 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: WD domain, G-beta repeat
Length: 345 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P62873 (Residues: 2-340; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Ligands and Environments
1 bound ligand:
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this EM entry.
Resolution:
3.3Å
Relevant EMDB volumes:
EMD-30608
Expression systems:
- Spodoptera frugiperda
- Escherichia coli BL21(DE3)
- Brevibacillus choshinensis
