› 7dc6

X-ray diffraction
2.68Å resolution

Giant panda MHC class I complexes

Released:
DOI: 10.2210/pdb7dc6/pdb
PDB entry 7dc6 coloured by chain, front view.
PDB entry 7dc6 coloured by chain, side view.
PDB entry 7dc6 coloured by chain, top view.
Source organisms:
Primary publication:
Crystal structure of the giant panda MHC class I complex: First insights into the viral peptide presentation profile in the bear family.
Yuan H, Ma L, Zhang L, Li X, Xia C
Protein Sci 29 2468-2481 (2020)
PMID: 33078460

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-105884 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 275 amino acids
Theoretical weight: 31.78 KDa
Source organism: Ailuropoda melanoleuca
Expression system: Escherichia coli
UniProt:
  • Canonical: B2KT53 (Residues: 25-299; Coverage: 81%)
Gene name: Aime-128
Sequence domains:
Beta-2-microglobulin Chains: B, D
Molecule details ›
Chains: B, D
Length: 99 amino acids
Theoretical weight: 11.58 KDa
Source organism: Ailuropoda melanoleuca
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A7N5K2L4 (Residues: 25-114; Coverage: 92%)
Gene name: B2M
Sequence domains: Immunoglobulin C1-set domain
Spike glycoprotein Chains: E, F
Molecule details ›
Chains: E, F
Length: 9 amino acids
Theoretical weight: 1.1 KDa
Source organism: Canine coronavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P10033 (Residues: 436-444; Coverage: 1%)
Gene names: 2, S

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P43212
Unit cell:
a: 173.677Å b: 173.677Å c: 84.346Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.268 0.266 0.291
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Crystal Structure of a Classical MHC Class I Molecule in Dogs; Comparison of DLA-88*0 and DLA-88*5 Category Molecules.
Sun et al. (2023)

1 mention without citation

Crystal structure of the giant panda MHC class I complex: First insights into the viral peptide presentation profile in the bear family.
Yuan et al. (2020)