› 7dci

X-ray diffraction
1.7Å resolution

Crystal structure of HSF2 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation

Released:
DOI: 10.2210/pdb7dci/pdb
PDB entry 7dci coloured by chain, front view.
PDB entry 7dci coloured by chain, side view.
PDB entry 7dci coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wei L, Wei L

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-121206 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Heat shock factor protein 2 Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 12.39 KDa
Source organism: Homo sapiens
Expression system: DNA satellites
UniProt:
  • Canonical: Q03933 (Residues: 7-110; Coverage: 19%)
Gene names: HSF2, HSTF2
Sequence domains: HSF-type DNA-binding
DNA (5'-D(*GP*GP*GP*AP*AP*TP*AP*TP*TP*CP*CP*C)-3') Chain: B
Molecule details ›
Chain: B
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Source organism: Homo sapiens
Expression system: DNA satellites

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: C2
Unit cell:
a: 92.268Å b: 38.472Å c: 38.654Å
α: 90° β: 100.74° γ: 90°
R-values:
R R work R free
0.181 0.179 0.209
Expression system: DNA satellites

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