PDB 7e1w structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reactions catalysed:

4 ferrocytochrome c + O(2) + 8 H(+)(Side 1) = 4 ferricytochrome c + 4 H(2)O(Side 2)

Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2)

Biochemical function:

oxidoreductase activity

Biological process:

proton transmembrane transport

Cellular component:

membrane

Sequence domains:

19 more domains

Structure analysis Details

Assembly composition:

hetero icosamer (preferred)

PDBe Complex ID:

PDB-CPX-106394 (preferred)

Entry contents:

10 distinct polypeptide molecules

Macromolecules (10 distinct):

cytochrome-c oxidase Chains: E, Q

Molecule details ›

Chains: E, Q
Length: 341 amino acids
Theoretical weight: 38.08 KDa
Source organism: Mycolicibacterium smegmatis MC2 51
UniProt:

Canonical: A0R057 (Residues: 1-341; Coverage: 100%)

Gene name: MSMEG_4268
Sequence domains: Cytochrome C oxidase subunit II, periplasmic domain

Cytochrome c oxidase subunit 1 Chains: F, R

Molecule details ›

Chains: F, R
Length: 575 amino acids
Theoretical weight: 64.16 KDa
Source organism: Mycolicibacterium smegmatis MC2 51

Probable cytochrome c oxidase subunit 3 Chains: G, S

Molecule details ›

Chains: G, S
Length: 203 amino acids
Theoretical weight: 22.2 KDa
Source organism: Mycolicibacterium smegmatis MC2 51
UniProt:

Canonical: A0R049 (Residues: 1-203; Coverage: 100%)

Gene name: MSMEG_4260
Sequence domains: Cytochrome c oxidase subunit III

Cytochrome c oxidase polypeptide 4 Chains: H, T

Molecule details ›

Chains: H, T
Length: 139 amino acids
Theoretical weight: 15.18 KDa
Source organism: Mycolicibacterium smegmatis MC2 51
UniProt:

Canonical: A0R056 (Residues: 1-139; Coverage: 100%)

Gene name: MSMEG_4267
Sequence domains: Cytochrome c oxidase subunit IV

Cytochrome c oxidase subunit CtaJ Chains: I, U

Molecule details ›

Chains: I, U
Length: 79 amino acids
Theoretical weight: 8.37 KDa
Source organism: Mycolicibacterium smegmatis MC2 51
UniProt:

Canonical: A0R1B6 (Residues: 1-79; Coverage: 100%)

Gene name: MSMEG_4693

Uncharacterized protein MSMEG_4692/MSMEI_4575 Chains: J, V

Molecule details ›

Chains: J, V
Length: 157 amino acids
Theoretical weight: 15.91 KDa
Source organism: Mycolicibacterium smegmatis MC2 51
UniProt:

Canonical: A0R1B5 (Residues: 1-157; Coverage: 100%)

Gene names: MSMEG_4692, MSMEI_4575
Sequence domains: Domain of unknown function (DUF5130)

Prokaryotic respiratory supercomplex associate factor 1 PRSAF1 Chains: D, P

Molecule details ›

Chains: D, P
Length: 100 amino acids
Theoretical weight: 11.33 KDa
Source organism: Mycolicibacterium smegmatis MC2 51

Cytochrome bc1 complex cytochrome b subunit Chains: B, N

Molecule details ›

Chains: B, N
Length: 549 amino acids
Theoretical weight: 61.08 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 51
UniProt:

Canonical: P9WP37 (Residues: 1-549; Coverage: 100%)

Gene names: MTCY190.07, Rv2196, qcrB
Sequence domains: Cytochrome b(N-terminal)/b6/petB

Cytochrome bc1 complex Rieske iron-sulfur subunit Chains: A, M

Molecule details ›

Chains: A, M
Length: 429 amino acids
Theoretical weight: 46.98 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 51
UniProt:

Canonical: P9WH23 (Residues: 1-429; Coverage: 100%)

Gene names: MTCY190.06, Rv2195, qcrA
Sequence domains:

Cytochrome bc1 complex cytochrome c subunit Chains: C, O

Molecule details ›

Chains: C, O
Length: 280 amino acids
Theoretical weight: 29.15 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 51
UniProt: