› 7e9v

X-ray diffraction
2.1Å resolution

The Crystal Structure of human UMP-CMP kinase from Biortus.

Released:
DOI: 10.2210/pdb7e9v/pdb
PDB entry 7e9v coloured by chain, front view.
PDB entry 7e9v coloured by chain, side view.
PDB entry 7e9v coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang F, Lin D, Wang R, Wei X, Shen Z, Wang M

Function and Biology Details

Reactions catalysed: 
ATP + (d)CMP = ADP + (d)CDP
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151632 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UMP-CMP kinase Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 24.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30085 (Residues: 1-196; Coverage: 100%)
Gene names: CMK, CMPK, CMPK1, UCK, UMK, UMPK
Sequence domains: Adenylate kinase

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P6522
Unit cell:
a: 61.926Å b: 61.926Å c: 225.397Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.205 0.25
Expression system: Escherichia coli

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