› 7el4

X-ray diffraction
2.11Å resolution

The crystal structure of p53p peptide fragment in complex with the N-terminal domain of MdmX

Released:
DOI: 10.2210/pdb7el4/pdb
PDB entry 7el4 coloured by chain, front view.
PDB entry 7el4 coloured by chain, side view.
PDB entry 7el4 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Cheng XY, Zhang BL, Li ZC, Kuang ZK, Su ZD

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127311 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53; Protein Mdm4 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 14.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P04637 (Residues: 23-29; Coverage: 2%)
  • Canonical: O15151 (Residues: 23-111; Coverage: 18%)
Gene names: MDM4, MDMX, P53, TP53

Ligands and Environments

2 bound ligands:
Ligand O4B 2 x O4B
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: I41
Unit cell:
a: 65.097Å b: 65.097Å c: 94.977Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.225
Expression system: Escherichia coli K-12

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