› 7f35

X-ray diffraction
2.6Å resolution

Crystal structure of anti S-gatifloxacin antibody Fab fragment in complex with S-gatifloxacin

Released:
DOI: 10.2210/pdb7f35/pdb
Model geometry
Fit model/data
PDB entry 7f35 coloured by chain, front view.
PDB entry 7f35 coloured by chain, side view.
PDB entry 7f35 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Conformational adaptability determining antibody recognition to distomer: structure analysis of enantioselective antibody against chiral drug gatifloxacin
Wang LT, Xie W, Jiao WY, Zhang C, Li X, Xu Z, Huang X, Lei HT, Shen X
RSC Adv 11 39534-39544 (2021)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214333 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Antibody Fab fragment light chain Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 218 amino acids
Theoretical weight: 24.13 KDa
Source organism: Mus musculus
Antibody Fab fragment heavy chain Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 218 amino acids
Theoretical weight: 23.47 KDa
Source organism: Mus musculus

Ligands and Environments

7 bound ligands:
Ligand GFN 3 x GFN
Ligand EDO 8 x EDO
Ligand NA 8 x NA
Ligand SO4 7 x SO4
Ligand GOL 2 x GOL
Ligand CL 1 x CL
Ligand CIT 1 x CIT
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P42212
Unit cell:
a: 184.071Å b: 184.071Å c: 100.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.235

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