7f7o

X-ray diffraction
2.8Å resolution

APC-Asef FP assay tracer

Released:
Entry authors: Yang X, Zhang J

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-150349 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Adenomatous polyposis coli protein Chain: A
Molecule details ›
Chain: A
Length: 335 amino acids
Theoretical weight: 37.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P25054 (Residues: 407-738; Coverage: 12%)
Gene names: APC, DP2.5
Sequence domains:
Tracer 7 Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.05 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P212121
Unit cell:
a: 57.234Å b: 71.619Å c: 83.873Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.287 0.285 0.328
Expression systems:
  • Escherichia coli
  • Not provided