Function and Biology Details
Reaction catalysed:
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Peptidase S3, togavirin
- Low-density lipoprotein (LDL) receptor class A repeat
- Flaviviral glycoprotein E, dimerisation domain
- LDL receptor-like superfamily
- Peptidase S1, PA clan, chymotrypsin-like fold
- Alphavirus E2 glycoprotein, domain C
- Alphavirus E2 glycoprotein, domain B
- Alphavirus E2 glycoprotein
8 more domains
Structure analysis Details
Assembly composition:
hetero icosamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138742 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Capsid protein
Molecule details ›
Chains: A, F, K, S
Length: 275 amino acids
Theoretical weight: 30.98 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
Expression system: Homo sapiens
UniProt:
Length: 275 amino acids
Theoretical weight: 30.98 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
Expression system: Homo sapiens
UniProt:
- Canonical:
P05674 (Residues: 1-275; Coverage: 22%)
Spike glycoprotein E1
Molecule details ›
Chains: B, C, G, O
Length: 442 amino acids
Theoretical weight: 47.95 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
Expression system: Homo sapiens
UniProt:
Length: 442 amino acids
Theoretical weight: 47.95 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
Expression system: Homo sapiens
UniProt:
- Canonical: P05674 (Residues: 813-1254; Coverage: 35%)
Low-density lipoprotein receptor class A domain-containing protein 3
Assembly protein E3
Spike glycoprotein E2
