Function and Biology Details
Reaction catalysed:
Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127405 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Serine palmitoyltransferase 1
Molecule details ›
Chains: A, D
Length: 473 amino acids
Theoretical weight: 52.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Aminotransferase class I and II
Length: 473 amino acids
Theoretical weight: 52.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
O15269 (Residues: 1-473; Coverage: 100%)
Sequence domains: Aminotransferase class I and II
Serine palmitoyltransferase 2
Molecule details ›
Chains: B, E
Length: 544 amino acids
Theoretical weight: 60.85 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Aminotransferase class I and II
Length: 544 amino acids
Theoretical weight: 60.85 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: O15270 (Residues: 1-544; Coverage: 97%)
Sequence domains: Aminotransferase class I and II
Serine palmitoyltransferase small subunit A
Molecule details ›
Chains: C, F
Length: 71 amino acids
Theoretical weight: 8.47 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Small subunit of serine palmitoyltransferase-like
Length: 71 amino acids
Theoretical weight: 8.47 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q969W0 (Residues: 1-71; Coverage: 100%)
Sequence domains: Small subunit of serine palmitoyltransferase-like
